The large scale economic collection of proteins is an increasingly important problem for the biotechnology industry. Since the cell lines used are living organisms, they must be fed with a complex growth medium. Separation of the desired protein from the fermentation broth poses challenges. An improved single-use centrifuge system has a single means for both feeding and collecting liquid streams aseptically from rotating components. Also, methods and apparatus for centrifugal separation of cells from cell culture media of large cell culture batches can be done by processing a large volume within a few hours, using pre-sterilized, single-use fluid path components. The apparatus uses a sealing approach that improves reliability while avoiding air contamination as well as shedding from mechanical seals. The risk of process liquid leaks is minimized. Advances in cell culture techniques have greatly increased the cell populations and titers of the target proteins in culture fluid. Most biopharmaceutical companies today are seeking ways to integrate single-use technologies into processing workflows.
Single Use Centrifuge Systems Market Intelligence with Competitive Landscape
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Single Use Centrifuge Systems Market Intelligence with Competitive Landscape September 26, 2018
CMEF2 September 28, 2018